Prince Frederik of Luxembourg Passes Away at 45

Prince Frederik’s Struggle: A Tribute to His Resilience

Prince Frederik of Luxembourg passed away on March 1, 2025, at the age of 22, after a lifelong battle with POLG mitochondrial disease, a rare genetic disorder.

Diagnosed at 14, Frederik established the POLG Foundation to raise awareness and fund research for this condition.

His father, Prince Robert, described him as a “superhero” for his strength and resilience.

POLG mitochondrial disease disrupts cellular energy production, leading to progressive organ failure.

Despite his illness, Frederik remained active in advocacy and inspired many with his positivity.

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